Professor, Department of Medicine
Tel: (604) 323-2547, ext. 10
Research Interests: Dr. Pelech’s research is focused on the mapping of protein kinase-based cell signalling pathways to identify diagnostic biomarkers and therapeutic targets for drug development for neurological disorders, cancer and diabetes. Experimental disease model systems under analyses relate to Alzheimer’s disease, Parkinson’s disease, multiple sclerosis, amyotrophic lateral sclerosis, cancer, and diabetes. Other systems under study relate to the regulation of meiotic maturation of oocytes, mitotic cell cycle progression in human tumour cells, and insulin signalling for metabolic control. Dr. Pelech’s lab has developed and utilized novel proteomics strategies involving multi-immunoblotting and microarrays with antibodies, cell/tissue lysates and purified protein kinase enzymes.
Honours and Awards: